Rapid Identification of Apolipoprotein E Genotypes by Multiplex Amplification Refractory Mutation System PCR and Capillary Gel Electrophoresis

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Rapid identification of apolipoprotein E genotypes by multiplex amplification refractory mutation system PCR and capillary gel electrophoresis.

References 1. Courjal F, Cuny M, Simony-Lafontaine J, Louason G, Speiser P, Zeillinger R, et al. Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors: definition of phenotypic groups. Cancer Res 1997;57: 4360–7. 2. Frye RA, Benz CA, Liu E. Detection of amplified oncogenes by differential polymerase chain reaction. Oncogene 1989;4:1153–7. 3. Siebert PD, Larrick JW....

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Rapid HLA typing by multiplex amplification refractory mutation system.

AIMS To detect HLA susceptibility and protective alleles associated with insulin dependent diabetes mellitus (IDDM) using a multiplex amplification refractory mutation system (ARMS). These include DR3 and DR4 alleles at the DRB1 locus, presence or absence of aspartic acid at position 57 (Asp-57) of the DQB1 locus, and presence or absence of arginine at position 52 (Arg-52) of the DQA1 locus. ...

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Analysis of apolipoprotein E genotypes by the Amplification Refractory Mutation System.

The Amplification Refractory Mutation System (ARMS) has been successfully applied to the detection of apolipoprotein (apo) E genotypes in human DNA extracted from peripheral blood. By using four allele-specific oligonucleotide primers and one common primer, one can identify the three common alleles of the apo E genetic polymorphism, epsilon 2, epsilon 3, and epsilon 4. The system amplifies two ...

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Genetic testing for familial Mediterranean fever in Austria by means of reverse-hybridization teststrips.

poproteins in mouse peritoneal macrophages. J Mol Med 2000;78:217–27. 3. Wenham PR, Sedky A, Spooner RJ. Apolipoprotein E phenotyping: a word of caution. Ann Clin Biochem 1991;28:599–605. 4. Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 1990;31:545–8. 5. Somsen GW, Welten HT, Mulder FP, Swart CW, Kema IP, de Jong...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 1999

ISSN: 0009-9147,1530-8561

DOI: 10.1093/clinchem/45.1.143